In a dilapidated and desolate part of Detroit with abandoned brick houses, the city's most dangerous criminals have found their abode. With no way to control the crime, the police have built a wall around the area to protect the rest of the city. For undercover agent Damian Collier (Paul Walker), every day is a battle against corruption. Ex-prisoner Lino (David Belle) also fights every day, but to live an honest life on the right side of the law. Their paths cross when drug lord Tremain (RZA) kidnaps Lino's girlfriend and the two opposites are suddenly forced to work together to prevent the entire city from exploding.